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Update on PARP Inhibitors in Breast Cancer

The single agent activity of PARP inhibitors (PARPi) in germline BRCA mutated (gBRCAm) breast and ovarian cancer suggests untapped potential for this new class of drug in breast cancer. The US Food and Drug Administration has approved three PARPi (olaparib, rucaparib, and niraparib) so far to treat...

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Detalhes bibliográficos
Publicado no:Curr Treat Options Oncol
Main Authors: Zimmer, Alexandra S., Gillard, Mitchell, Lipkowitz, Stanley, Lee, Jung-Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7430202/
https://ncbi.nlm.nih.gov/pubmed/29644491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11864-018-0540-2
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