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Amino acid-dependent control of mTORC1 signaling: a variety of regulatory modes

The mechanistic target of rapamycin complex 1 (mTORC1) is an essential regulator of cell growth and metabolism through the modulation of protein and lipid synthesis, lysosome biogenesis, and autophagy. The activity of mTORC1 is dynamically regulated by several environmental cues, including amino aci...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Takahara, Terunao, Amemiya, Yuna, Sugiyama, Risa, Maki, Masatoshi, Shibata, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429791/
https://ncbi.nlm.nih.gov/pubmed/32799865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00679-2
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