Lactobacillus sakei suppresses collagen-induced arthritis and modulates the differentiation of T helper 17 cells and regulatory B cells

BACKGROUND: To evaluate the immunomodulatory effect of Lactobacillus sakei in a mouse model of rheumatoid arthritis (RA) and in human immune cells. METHODS: We evaluated whether L. sakei reduced the severity of collagen-induced arthritis (CIA) and modulated interleukin (IL)-17 and IL-10 levels, as w...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: Jhun, Jooyeon, Min, Hong Ki, Ryu, Jaeyoon, Lee, Seon-Yeong, Ryu, Jun-Geol, Choi, Jeong Won, Na, Hyun Sik, Lee, Seung Yoon, Jung, Yunju, Park, Sang-Jun, Park, Myeong Soo, Kwon, Bin, Ji, Geun Eog, Cho, Mi-La, Park, Sung-Hwan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429687/
https://ncbi.nlm.nih.gov/pubmed/32799896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02477-8
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