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Stochastic allelic expression as trigger for contractile imbalance in hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM), the most common inherited cardiac disease, is caused by several mostly heterozygous mutations in sarcomeric genes. Hallmarks of HCM are cardiomyocyte and myofibrillar disarray and hypertrophy and fibrosis of the septum and the left ventricle. To date, a pathomechan...
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| Udgivet i: | Biophys Rev |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7429642/ https://ncbi.nlm.nih.gov/pubmed/32661905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-020-00719-z |
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