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Altered force generation and cell-to-cell contractile imbalance in hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is mainly caused by mutations in sarcomeric proteins. Thirty to forty percent of identified mutations are found in the ventricular myosin heavy chain (β-MyHC). A common mechanism explaining how numerous mutations in several different proteins induce a similar HCM-ph...
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| Publicado no: | Pflugers Arch |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6475633/ https://ncbi.nlm.nih.gov/pubmed/30740621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-019-02260-9 |
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