Tau contributes to sevoflurane-induced neurocognitive impairment in neonatal mice

BACKGROUND: Sevoflurane anesthesia induces Tau phosphorylation and cognitive impairment in neonatal but not in adult mice. Here we tested the hypothesis that differences in brain Tau amounts and in the activity of mitochondria-ATP-Nuak1-Tau cascade between the neonatal and adult mice contribute to t...

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Publicado en:Anesthesiology
Main Authors: Yu, Yang, Yang, Yongyan, Tan, Hong, Boukhali, Myriam, Khatri, Ashok, Yu, Yonghao, Hua, Fuzhou, Liu, Ling, Li, Mengzhu, Yang, Guang, Dong, Yuanlin, Zhang, Yiying, Haas, Wilhelm, Xie, Zhongcong
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429299/
https://ncbi.nlm.nih.gov/pubmed/32701572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000003452
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