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D-Retro Inverso (DRI) Amylin and the Stability of Amylin Fibrils

Motivated by the role that amylin aggregates play in type-II diabetes, we compare the stability of regular amylin fibrils with the stability of fibrils where L-amino acid chains are replaced by D–Retro Inverso (DRI) amylin, i.e., peptides where the sequence of amino acids is reversed, and at the sam...

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Foilsithe in:J Chem Theory Comput
Main Authors: Pandey, Preeti, Nguyen, Natalie, Hansmann, Ulrich H.E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429257/
https://ncbi.nlm.nih.gov/pubmed/32667784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.0c00523
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