Advanced Glycation End Products Induce Vascular Smooth Muscle Cell-Derived Foam Cell Formation and Transdifferentiate to a Macrophage-Like State

BACKGROUND: Advanced glycation end products play an important role in diabetic atherosclerosis. The effects of advanced glycation end products (AGEs) on vascular smooth muscle cell- (VSMC-) derived foam cell formation and phenotypic transformation are unknown. METHODS: Serological and histological s...

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Veröffentlicht in:Mediators Inflamm
Hauptverfasser: Bao, Zhengyang, Li, Lihua, Geng, Yue, Yan, Jinchuan, Dai, Zhiyin, Shao, Chen, Sun, Zhen, Jing, Lele, Pang, Qiwen, Zhang, Lili, Wang, Xiaodong, Wang, Zhongqun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428884/
https://ncbi.nlm.nih.gov/pubmed/32831637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6850187
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