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Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE)

Tubulointerstitial disease, a prominent phenomenon in diabetic nephropathy, correlates with decline in renal function. The underlying pathogenic link between chronic hyperglycemia and the development of tubulointerstitial injury has not been fully elucidated, but myofibroblast formation represents a...

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Detalhes bibliográficos
Main Authors: Oldfield, Matthew D., Bach, Leon A., Forbes, Josephine M., Nikolic-Paterson, David, McRobert, Anne, Thallas, Vicki, Atkins, Robert C., Osicka, Tanya, Jerums, George, Cooper, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC209461/
https://ncbi.nlm.nih.gov/pubmed/11748269
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