Advanced Glycation End Products Induce Tubular Epithelial-Myofibroblast Transition through the RAGE-ERK1/2 MAP Kinase Signaling Pathway

Advanced glycation end products (AGEs) have been shown to play a role in tubular epithelial-myofibroblast transdifferentiation (TEMT) in diabetic nephropathy, but the intracellular signaling pathway remains unknown. We report here that AGEs signal through the receptor for AGEs (RAGE) to induce TEMT,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Li, Jin H., Wang, Wansheng, Huang, Xiao R., Oldfield, Matthew, Schmidt, Ann M., Cooper, Mark E., Lan, Hui Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2004
Aiheet:
Regular Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615341/
https://ncbi.nlm.nih.gov/pubmed/15039226
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