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Vascular endothelial growth factor modified macrophages transdifferentiate into endothelial-like cells and decrease foam cell formation

Macrophages are largely involved in the whole process of atherosclerosis from an initiation lesion to an advanced lesion. Endothelial disruption is the initial step and macrophage-derived foam cells are the hallmark of atherosclerosis. Promotion of vascular integrity and inhibition of foam cell form...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Yan, Dan, He, Yujuan, Dai, Jun, Yang, Lili, Wang, Xiaoyan, Ruan, Qiurong
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479018/
https://ncbi.nlm.nih.gov/pubmed/28536311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170002
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