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Vascular endothelial growth factor modified macrophages transdifferentiate into endothelial-like cells and decrease foam cell formation

Macrophages are largely involved in the whole process of atherosclerosis from an initiation lesion to an advanced lesion. Endothelial disruption is the initial step and macrophage-derived foam cells are the hallmark of atherosclerosis. Promotion of vascular integrity and inhibition of foam cell form...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biosci Rep
Hauptverfasser: Yan, Dan, He, Yujuan, Dai, Jun, Yang, Lili, Wang, Xiaoyan, Ruan, Qiurong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479018/
https://ncbi.nlm.nih.gov/pubmed/28536311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170002
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