Oxygen Exposure During Cardiopulmonary Resuscitation Is Associated With Cerebral Oxidative Injury in a Randomized, Blinded, Controlled, Preclinical Trial

BACKGROUND: Hyperoxia during cardiopulmonary resuscitation (CPR) may lead to oxidative injury from mitochondrial‐derived reactive oxygen species, despite guidelines recommending 1.0 inspired oxygen during CPR. We hypothesized exposure to 1.0 inspired oxygen during CPR would result in cerebral hypero...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Marquez, Alexandra M., Morgan, Ryan W., Ko, Tiffany, Landis, William P., Hefti, Marco M., Mavroudis, Constantine D., McManus, Meagan J., Karlsson, Michael, Starr, Jonathan, Roberts, Anna L., Lin, Yuxi, Nadkarni, Vinay, Licht, Daniel J., Berg, Robert A., Sutton, Robert M., Kilbaugh, Todd J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428577/
https://ncbi.nlm.nih.gov/pubmed/32321350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.015032
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