Haemodynamic-directed cardiopulmonary resuscitation promotes mitochondrial fusion and preservation of mitochondrial mass after successful resuscitation in a pediatric porcine model

OBJECTIVE: Cerebral mitochondrial dysfunction is a key mediator of neurologic injury following cardiac arrest (CA) and is regulated by the balance of fusion and fission (mitochondrial dynamics). Under stress, fission can decrease mitochondrial mass and signal apoptosis, while fusion promotes oxidati...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Resusc Plus
Egile Nagusiak: Senthil, Kumaran, Morgan, Ryan W., Hefti, Marco M., Karlsson, Michael, Lautz, Andrew J., Mavroudis, Constantine D., Ko, Tiffany, Nadkarni, Vinay M., Ehinger, Johannes, Berg, Robert A., Sutton, Robert M., McGowan, Francis X., Kilbaugh, Todd J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2021
Gaiak:
Experimental Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244484/
https://ncbi.nlm.nih.gov/pubmed/34223382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.resplu.2021.100124
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