Noncanonical function of an autophagy protein prevents spontaneous Alzheimer’s disease

Noncanonical functions of autophagy proteins have been implicated in neurodegenerative conditions, including Alzheimer’s disease (AD). The WD domain of the autophagy protein Atg16L is dispensable for canonical autophagy but required for its noncanonical functions. Two-year-old mice lacking this doma...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Adv
Autori principali: Heckmann, Bradlee L., Teubner, Brett J. W., Boada-Romero, Emilio, Tummers, Bart, Guy, Clifford, Fitzgerald, Patrick, Mayer, Ulrike, Carding, Simon, Zakharenko, Stanislav S., Wileman, Thomas, Green, Douglas R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7428329/
https://ncbi.nlm.nih.gov/pubmed/32851186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb9036
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi