Unique molecular signatures of antiviral memory CD8(+) T cells associated with asymptomatic recurrent ocular herpes

The nature of antiviral CD8(+) T cells associated with protective and pathogenic herpes simplex virus type 1 (HSV-1) infections remains unclear. We compared the transcriptome, phenotype, and function of memory CD8(+) T cells, sharing the same HSV-1 epitope-specificities, from infected HLA-A*0201 pos...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Prakash, Swayam, Roy, Soumyabrata, Srivastava, Ruchi, Coulon, Pierre-Gregoire, Dhanushkodi, Nisha R., Vahed, Hawa, Jankeel, Allen, Geertsema, Roger, Amezquita, Cassandra, Nguyen, Lan, Messaoudi, Ilhem, Burkhardt, Amanda M., BenMohamed, Lbachir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427992/
https://ncbi.nlm.nih.gov/pubmed/32796943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70673-z
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