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Up-Regulation of Multiple CD8(+) T Cell Exhaustion Pathways is Associated to Recurrent Ocular Herpes Simplex Virus Type 1 Infection

A large proportion of the world’s population harbors latent herpes simplex virus type 1 (HSV-1). Crosstalk between antiviral CD8(+) T cells and HSV-1 appear to control latency/reactivation cycles. We found that, compared to healthy asymptomatic (ASYMP) individuals, in symptomatic (SYMP) patients the...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Coulon, Pierre-Grégoire, Roy, Soumyabrata, Prakash, Swayam, Srivastava, Ruchi, Dhanushkodi, Nisha, Salazar, Stephanie, Amezquita, Cassandra, Nguyen, Lan, Vahed, Hawa, Nguyen, Angela M., Warsi, Wasay R., Ye, Caitlin, Carlos-Cruz, Edgar A., Mai, Uyen T., BenMohamed, Lbachir
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343593/
https://ncbi.nlm.nih.gov/pubmed/32540992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000131
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