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Deoxyshikonin Inhibits Viability and Glycolysis by Suppressing the Akt/mTOR Pathway in Acute Myeloid Leukemia Cells

Deoxyshikonin was reported to exhibit an anti-tumor effect in colorectal cancer. However, no studies are available to illustrate the effect of deoxyshikonin on acute myeloid leukemia (AML). The effects of deoxyshikonin on viability, apoptosis, caspase-3/7 activity, and cytochrome (Cyt) C expression...

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Publicat a:Front Oncol
Autors principals: Wu, Huijuan, Zhao, Hongmian, Chen, Li
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427633/
https://ncbi.nlm.nih.gov/pubmed/32850379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01253
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