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Optogenetic control of protein binding using light-switchable nanobodies

A growing number of optogenetic tools have been developed to reversibly control binding between two engineered protein domains. In contrast, relatively few tools confer light-switchable binding to a generic target protein of interest. Such a capability would offer substantial advantages, enabling ph...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Gil, Agnieszka A., Carrasco-López, César, Zhu, Liyuan, Zhao, Evan M., Ravindran, Pavithran T., Wilson, Maxwell Z., Goglia, Alexander G., Avalos, José L., Toettcher, Jared E.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426870/
https://ncbi.nlm.nih.gov/pubmed/32792536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17836-8
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