A Two-Way Interaction between Methotrexate and the Gut Microbiota of Male Sprague–Dawley Rats

[Image: see text] Methotrexate (MTX) is a chemotherapeutic agent that can cause a range of toxic side effects including gastrointestinal damage, hepatotoxicity, myelosuppression, and nephrotoxicity and has potentially complex interactions with the gut microbiome. Following untargeted UPLC-qtof-MS an...

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Detalhes bibliográficos
Publicado no:J Proteome Res
Main Authors: Letertre, Marine P. M., Munjoma, Nyasha, Wolfer, Kate, Pechlivanis, Alexandros, McDonald, Julie A. K., Hardwick, Rhiannon N., Cherrington, Nathan J., Coen, Muireann, Nicholson, Jeremy K., Hoyles, Lesley, Swann, Jonathan R., Wilson, Ian D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7426014/
https://ncbi.nlm.nih.gov/pubmed/32544340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.0c00230
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