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Multi-arm Avidin nano-construct for intra-cartilage delivery of small molecule drugs

Targeted drug delivery to joint tissues like cartilage remains a challenge that has prevented clinical translation of promising osteoarthritis (OA) drugs. Local intra-articular (IA) injections of drugs suffer from rapid clearance from the joint space and slow diffusive transport through the dense, a...

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Podrobná bibliografie
Vydáno v:J Control Release
Hlavní autoři: He, Tengfei, Zhang, Chenzhen, Vedadghavami, Armin, Mehta, Shikhar, Clark, Heather A., Porter, Ryan M., Bajpayee, Ambika G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424591/
https://ncbi.nlm.nih.gov/pubmed/31843642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.12.020
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