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Cartilage Penetrating Cationic Peptide Carriers for Applications in Drug Delivery to Avascular Negatively Charged Tissues

Drug delivery to avascular, negatively charged tissues like cartilage remains a challenge. The constant turnover of synovial fluid results in short residence time of administered drugs in the joint space and the dense negatively charged matrix of cartilage hinders their diffusive transport. Drugs ar...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Vedadghavami, Armin, Wagner, Erica K., Mehta, Shikhar, He, Tengfei, Zhang, Chenzhen, Bajpayee, Ambika G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551323/
https://ncbi.nlm.nih.gov/pubmed/30529083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.12.004
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