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Milk Exosomes with Enhanced Mucus Penetrability for Oral Delivery of siRNA

Bovine milk-derived exosomes have recently emerged as a promising nano-vehicle for the encapsulation and delivery of macromolecular biotherapeutics. Here we engineer high purity bovine milk exosomes (mExo) with modular surface tunability for oral delivery of small interfering RNA (siRNA). We utilize...

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Detalhes bibliográficos
Publicado no:Biomater Sci
Main Authors: Warren, Matthew R., Zhang, Chenzhen, Vedadghavami, Armin, Bokvist, Krister, Dhal, Pradeep K., Bajpayee, Ambika G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8205963/
https://ncbi.nlm.nih.gov/pubmed/33367332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0bm01497d
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