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Cartilage Penetrating Cationic Peptide Carriers for Applications in Drug Delivery to Avascular Negatively Charged Tissues

Drug delivery to avascular, negatively charged tissues like cartilage remains a challenge. The constant turnover of synovial fluid results in short residence time of administered drugs in the joint space and the dense negatively charged matrix of cartilage hinders their diffusive transport. Drugs ar...

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Dettagli Bibliografici
Pubblicato in:Acta Biomater
Autori principali: Vedadghavami, Armin, Wagner, Erica K., Mehta, Shikhar, He, Tengfei, Zhang, Chenzhen, Bajpayee, Ambika G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551323/
https://ncbi.nlm.nih.gov/pubmed/30529083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2018.12.004
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