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Charge based intra-cartilage delivery of single dose dexamethasone using Avidin nano-carriers suppresses cytokine-induced catabolism long term
OBJECTIVE: Avidin exhibits ideal characteristics for targeted intra-cartilage drug delivery: its small size and optimal positive charge enable rapid penetration through full-thickness cartilage and electrostatic binding interactions that give long half-lives in-vivo. Here we conjugated Avidin with d...
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| Publicado no: | Osteoarthritis Cartilage |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695287/ https://ncbi.nlm.nih.gov/pubmed/26211608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.07.010 |
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