Ticagrelor Conditioning Effects Are Not Additive to Cardioprotection Induced by Direct NLRP3 Inflammasome Inhibition: Role of RISK, NLRP3, and Redox Cascades

Inhibition of either P2Y12 receptor or the nucleotide-binding oligomerization domain- (NOD-) like receptor pyrin domain containing 3 (NLRP3) inflammasome provides cardioprotective effects. Here, we investigate whether direct NLRP3 inflammasome inhibition exerts additive effects on myocardial protect...

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Veröffentlicht in:Oxid Med Cell Longev
Hauptverfasser: Penna, Claudia, Aragno, Manuela, Cento, Alessia Sofia, Femminò, Saveria, Russo, Isabella, Bello, Federica Dal, Chiazza, Fausto, Collotta, Debora, Alves, Gustavo Ferreira, Bertinaria, Massimo, Zicola, Elisa, Mercurio, Valentina, Medana, Claudio, Collino, Massimo, Pagliaro, Pasquale
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7424511/
https://ncbi.nlm.nih.gov/pubmed/32832010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9219825
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