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Maladaptive Modulations of NLRP3 Inflammasome and Cardioprotective Pathways Are Involved in Diet-Induced Exacerbation of Myocardial Ischemia/Reperfusion Injury in Mice

Excessive fatty acids and sugars intake is known to affect the development of cardiovascular diseases, including myocardial infarction. However, the underlying mechanisms are ill defined. Here we investigated the balance between prosurvival and detrimental pathways within the heart of C57Bl/6 male m...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Mastrocola, Raffaella, Collino, Massimo, Penna, Claudia, Nigro, Debora, Chiazza, Fausto, Fracasso, Veronica, Tullio, Francesca, Alloatti, Giuseppe, Pagliaro, Pasquale, Aragno, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691622/
https://ncbi.nlm.nih.gov/pubmed/26788246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3480637
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