Bacterial polyphosphates interfere with the innate host defense to infection

Polyphosphates are linear polymers and ubiquitous metabolites. Bacterial polyphosphates are long chains of hundreds of phosphate units. Here, we report that mouse survival of peritoneal Escherichia coli sepsis is compromised by long-chain polyphosphates, and improves with bacterial polyphosphatekina...

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Vydáno v:Nat Commun
Hlavní autoři: Roewe, Julian, Stavrides, Georgios, Strueve, Marcel, Sharma, Arjun, Marini, Federico, Mann, Amrit, Smith, Stephanie A., Kaya, Ziya, Strobl, Birgit, Mueller, Mathias, Reinhardt, Christoph, Morrissey, James H., Bosmann, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423913/
https://ncbi.nlm.nih.gov/pubmed/32788578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17639-x
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