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Polyphosphate as a Target for Interference With Inflammation and Thrombosis

Activated platelets and mast cells expose the inorganic polymer, polyphosphate (polyP) on their surfaces. PolyP initiates procoagulant and proinflammatory reactions and the polymer has been recognized as a therapeutic target for interference with blood coagulation and vascular hyperpermeability. Pol...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Mailer, Reiner K. W., Hänel, Lorena, Allende, Mikel, Renné, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499166/
https://ncbi.nlm.nih.gov/pubmed/31106204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2019.00076
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