Bacterial polyphosphates interfere with the innate host defense to infection

Polyphosphates are linear polymers and ubiquitous metabolites. Bacterial polyphosphates are long chains of hundreds of phosphate units. Here, we report that mouse survival of peritoneal Escherichia coli sepsis is compromised by long-chain polyphosphates, and improves with bacterial polyphosphatekina...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Roewe, Julian, Stavrides, Georgios, Strueve, Marcel, Sharma, Arjun, Marini, Federico, Mann, Amrit, Smith, Stephanie A., Kaya, Ziya, Strobl, Birgit, Mueller, Mathias, Reinhardt, Christoph, Morrissey, James H., Bosmann, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423913/
https://ncbi.nlm.nih.gov/pubmed/32788578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17639-x
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