Beading of injured axons driven by tension- and adhesion-regulated membrane shape instability

The formation of multiple beads along an injured axon will lead to blockage of axonal transport and eventually neuron death, and this has been widely recognized as a hallmark of nervous system degeneration. Nevertheless, the underlying mechanisms remain poorly understood. Here, we report a combined...

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Detalles Bibliográficos
Publicado en:J R Soc Interface
Autores principales: Shao, Xueying, Sørensen, Maja Højvang, Xia, Xingyu, Fang, Chao, Hui, Tsz Hin, Chang, Raymond Chuen Chung, Chu, Zhiqin, Lin, Yuan
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society 2020
Materias:
Life Sciences–Physics interface
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423423/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0331
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