Beading of injured axons driven by tension- and adhesion-regulated membrane shape instability

The formation of multiple beads along an injured axon will lead to blockage of axonal transport and eventually neuron death, and this has been widely recognized as a hallmark of nervous system degeneration. Nevertheless, the underlying mechanisms remain poorly understood. Here, we report a combined...

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Publicat a:J R Soc Interface
Autors principals: Shao, Xueying, Sørensen, Maja Højvang, Xia, Xingyu, Fang, Chao, Hui, Tsz Hin, Chang, Raymond Chuen Chung, Chu, Zhiqin, Lin, Yuan
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2020
Matèries:
Life Sciences–Physics interface
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423423/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2020.0331
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