The Roles of Microtubules and Membrane Tension in Axonal Beading, Retraction, and Atrophy

Axonal beading, or the formation of a series of swellings along the axon, and retraction are commonly observed shape transformations that precede axonal atrophy in Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative conditions. The mechanisms driving these morphological transformat...

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Publicat a:Biophys J
Autors principals: Datar, Anagha, Ameeramja, Jaishabanu, Bhat, Alka, Srivastava, Roli, Mishra, Ashish, Bernal, Roberto, Prost, Jacques, Callan-Jones, Andrew, Pullarkat, Pramod A.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2019
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731471/
https://ncbi.nlm.nih.gov/pubmed/31427070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.046
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