The Roles of Microtubules and Membrane Tension in Axonal Beading, Retraction, and Atrophy

Axonal beading, or the formation of a series of swellings along the axon, and retraction are commonly observed shape transformations that precede axonal atrophy in Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative conditions. The mechanisms driving these morphological transformat...

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Vydáno v:Biophys J
Hlavní autoři: Datar, Anagha, Ameeramja, Jaishabanu, Bhat, Alka, Srivastava, Roli, Mishra, Ashish, Bernal, Roberto, Prost, Jacques, Callan-Jones, Andrew, Pullarkat, Pramod A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731471/
https://ncbi.nlm.nih.gov/pubmed/31427070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.07.046
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