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TRIBE editing reveals specific mRNA targets of eIF4E-BP in Drosophila and in mammals
4E-BP (eIF4E-BP) represses translation initiation by binding to the 5′ cap–binding protein eIF4E and inhibiting its activity. Although 4E-BP has been shown to be important in growth control, stress response, cancer, neuronal activity, and mammalian circadian rhythms, it is not understood how it pref...
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| Publicado en: | Sci Adv |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Association for the Advancement of Science
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7423359/ https://ncbi.nlm.nih.gov/pubmed/32851185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb8771 |
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