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Hijacking an RNA-editing enzyme to identify cell-specific targets of RNA-binding proteins
RNA transcripts are bound and regulated by RNA-binding proteins (RBPs). Current methods for identifying in vivo targets of a RBP are imperfect and not amenable to examining small numbers of cells. To address these issues, we developed TRIBE (Targets of RNA-binding proteins Identified By Editing), a...
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| Publié dans: | Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5027142/ https://ncbi.nlm.nih.gov/pubmed/27040499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.03.007 |
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