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Mechanistic implications of enhanced editing by a HyperTRIBE RNA-binding protein

We previously developed TRIBE, a method for the identification of cell-specific RNA-binding protein targets. TRIBE expresses an RBP of interest fused to the catalytic domain (cd) of the RNA-editing enzyme ADAR and performs adenosine-to-inosine editing on RNA targets of the RBP. However, target ident...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Xu, Weijin, Rahman, Reazur, Rosbash, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769745/
https://ncbi.nlm.nih.gov/pubmed/29127211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064691.117
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