Hepatocyte peroxisome proliferator-activated receptor α regulates bile acid synthesis and transport

Peroxisome proliferator-activated receptor alpha (PPARα) controls lipid homeostasis through regulation of lipid transport and catabolism. PPARα activators are clinically used for hyperlipidemia treatment. The role of PPARα in bile acid (BA) homeostasis is beginning to emerge. Herein, Ppara-null and...

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Publicado en:Biochim Biophys Acta Mol Cell Biol Lipids
Main Authors: Xie, Cen, Takahashi, Shogo, Brocker, Chad N., He, Shijun, Chen, Li, Xie, Guomin, Jang, Katrina, Gao, Xiaoxia, Krausz, Kristopher W., Qu, Aijuan, Levi, Moshe, Gonzalez, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423166/
https://ncbi.nlm.nih.gov/pubmed/31195146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2019.05.014
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