Hepatocyte Peroxisome Proliferator–Activated Receptor α Enhances Liver Regeneration after Partial Hepatectomy in Mice

Peroxisome proliferator–activated receptor α (PPARα) is a key nuclear receptor involved in the control of lipid homeostasis. In rodents, PPARα is also a potent hepatic mitogen. Hepatocyte-specific disruption of PPARα inhibits agonist-induced hepatocyte proliferation; however, little is known about t...

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Bibliographic Details
Published in:Am J Pathol
Main Authors: Xie, Guomin, Yin, Shi, Zhang, Zhenzhen, Qi, Dan, Wang, Xia, Kim, Donghwan, Yagai, Tomoki, Brocker, Chad N., Wang, Yan, Gonzalez, Frank J., Wang, Hua, Qu, Aijuan
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6593252/
https://ncbi.nlm.nih.gov/pubmed/30448405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.10.009
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