Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet

The incidence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, including in Asian countries. We reported that the hepatic expression of bile salt export pump (BSEP) was downregulated in patients with NASH, suggesting that BSEP is involved in the pathogenesis of NASH. To identify the u...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Okushin, Kazuya, Tsutsumi, Takeya, Ikeuchi, Kazuhiko, Kado, Akira, Enooku, Kenichiro, Fujinaga, Hidetaka, Yamauchi, Naoko, Ushiku, Tetsuo, Moriya, Kyoji, Yotsuyanagi, Hiroshi, Koike, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423142/
https://ncbi.nlm.nih.gov/pubmed/32785220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234750
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