Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet

The incidence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, including in Asian countries. We reported that the hepatic expression of bile salt export pump (BSEP) was downregulated in patients with NASH, suggesting that BSEP is involved in the pathogenesis of NASH. To identify the u...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Okushin, Kazuya, Tsutsumi, Takeya, Ikeuchi, Kazuhiko, Kado, Akira, Enooku, Kenichiro, Fujinaga, Hidetaka, Yamauchi, Naoko, Ushiku, Tetsuo, Moriya, Kyoji, Yotsuyanagi, Hiroshi, Koike, Kazuhiko
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423142/
https://ncbi.nlm.nih.gov/pubmed/32785220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234750
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