Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet

The incidence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, including in Asian countries. We reported that the hepatic expression of bile salt export pump (BSEP) was downregulated in patients with NASH, suggesting that BSEP is involved in the pathogenesis of NASH. To identify the u...

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Vydáno v:PLoS One
Hlavní autoři: Okushin, Kazuya, Tsutsumi, Takeya, Ikeuchi, Kazuhiko, Kado, Akira, Enooku, Kenichiro, Fujinaga, Hidetaka, Yamauchi, Naoko, Ushiku, Tetsuo, Moriya, Kyoji, Yotsuyanagi, Hiroshi, Koike, Kazuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423142/
https://ncbi.nlm.nih.gov/pubmed/32785220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234750
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