Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet

The incidence of nonalcoholic steatohepatitis (NASH) is increasing worldwide, including in Asian countries. We reported that the hepatic expression of bile salt export pump (BSEP) was downregulated in patients with NASH, suggesting that BSEP is involved in the pathogenesis of NASH. To identify the u...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Okushin, Kazuya, Tsutsumi, Takeya, Ikeuchi, Kazuhiko, Kado, Akira, Enooku, Kenichiro, Fujinaga, Hidetaka, Yamauchi, Naoko, Ushiku, Tetsuo, Moriya, Kyoji, Yotsuyanagi, Hiroshi, Koike, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423142/
https://ncbi.nlm.nih.gov/pubmed/32785220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0234750
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