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Striking Similarities between CDRs in Some mAbs That Neutralize COVID-19

[Image: see text] Four of five different monoclonal antibodies (mAbs) that have been crystallized in complex with the receptor binding domain (RBD) of the SARS-CoV-2 spike protein (S) have remarkably similar primary and secondary loop structures at the heavy chain complementarity-determining regions...

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Foilsithe in:ACS Med Chem Lett
Main Authors: Mi, Tianxiong, Burgess, Kevin
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2020
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7423023/
https://ncbi.nlm.nih.gov/pubmed/32934769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00409
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