Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity

Environmental factors are the largest contributors to cardiovascular disease. Here, we show that cardiac organoids incorporating an oxygen-diffusion gradient and stimulated via the neurotransmitter norepinephrine can structurally model the human heart after myocardial infarction (mimicking the gradi...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Biomed Eng
Egile Nagusiak: Richards, Dylan J., Li, Yang, Kerr, Charles M., Yao, Jenny, Beeson, Gyda C., Coyle, Robert C., Chen, Xun, Jia, Jia, Damon, Brooke, Wilson, Robert, Hazard, E. Starr, Hardiman, Gary, Menick, Donald, Beeson, Craig C., Yao, Hai, Ye, Tong, Mei, Ying
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422941/
https://ncbi.nlm.nih.gov/pubmed/32284552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-0539-4
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