Human cardiac organoids for the modelling of myocardial infarction and drug cardiotoxicity

Environmental factors are the largest contributors to cardiovascular disease. Here, we show that cardiac organoids incorporating an oxygen-diffusion gradient and stimulated via the neurotransmitter norepinephrine can structurally model the human heart after myocardial infarction (mimicking the gradi...

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Bibliografski detalji
Izdano u:Nat Biomed Eng
Glavni autori: Richards, Dylan J., Li, Yang, Kerr, Charles M., Yao, Jenny, Beeson, Gyda C., Coyle, Robert C., Chen, Xun, Jia, Jia, Damon, Brooke, Wilson, Robert, Hazard, E. Starr, Hardiman, Gary, Menick, Donald, Beeson, Craig C., Yao, Hai, Ye, Tong, Mei, Ying
Format: Artigo
Jezik:Inglês
Izdano: 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422941/
https://ncbi.nlm.nih.gov/pubmed/32284552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-020-0539-4
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