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Gene Expression Profile and Acute Gene Expression Response to Sclerostin Inhibition in Osteogenesis Imperfecta Bone

Sclerostin antibody (SclAb) therapy has been suggested as a novel therapeutic approach toward addressing the fragility phenotypic of osteogenesis imperfecta (OI). Observations of cellular and transcriptional responses to SclAb in OI have been limited to mouse models of the disorder, leaving a paucit...

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Detalhes bibliográficos
Publicado no:JBMR Plus
Main Authors: Surowiec, Rachel K, Battle, Lauren F, Schlecht, Stephen H, Wojtys, Edward M, Caird, Michelle S, Kozloff, Kenneth M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422710/
https://ncbi.nlm.nih.gov/pubmed/32803109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10377
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