Programmable inhibition and detection of RNA viruses using Cas13

The CRISPR effector Cas13 could be an effective antiviral for single-stranded RNA (ssRNA) viruses because it programmably cleaves RNAs complementary to its CRISPR RNA (crRNA). Here, we computationally identify thousands of potential Cas13 crRNA target sites in hundreds of ssRNA viral species that ca...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Freije, Catherine A., Myhrvold, Cameron, Boehm, Chloe K., Lin, Aaron E., Welch, Nicole L., Carter, Amber, Metsky, Hayden C., Luo, Cynthia Y., Abudayyeh, Omar O., Gootenberg, Jonathan S., Yozwiak, Nathan L., Zhang, Feng, Sabeti, Pardis C.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7422627/
https://ncbi.nlm.nih.gov/pubmed/31607545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.09.013
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker