Structural, in silico, and functional analysis of a Disabled-2-derived peptide for recognition of sulfatides

Disabled-2 (Dab2) is an adaptor protein that regulates the extent of platelet aggregation by two mechanisms. In the first mechanism, Dab2 intracellularly downregulates the integrin α(IIb)β(3) receptor, converting it to a low affinity state for adhesion and aggregation processes. In the second mechan...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Song, Wei, Gottschalk, Carter J., Tang, Tuo-Xian, Biscardi, Andrew, Ellena, Jeffrey F., Finkielstein, Carla V., Brown, Anne M., Capelluto, Daniel G. S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7421900/
https://ncbi.nlm.nih.gov/pubmed/32782308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70478-0
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