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Structural, in silico, and functional analysis of a Disabled-2-derived peptide for recognition of sulfatides
Disabled-2 (Dab2) is an adaptor protein that regulates the extent of platelet aggregation by two mechanisms. In the first mechanism, Dab2 intracellularly downregulates the integrin α(IIb)β(3) receptor, converting it to a low affinity state for adhesion and aggregation processes. In the second mechan...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7421900/ https://ncbi.nlm.nih.gov/pubmed/32782308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-70478-0 |
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