A carregar...
Membrane targeting of TIRAP is negatively regulated by phosphorylation in its phosphoinositide-binding motif
Pathogen-activated Toll-like receptors (TLRs), such as TLR2 and TLR4, dimerize and move laterally across the plasma membrane to phosphatidylinositol (4,5)-bisphosphate-enriched domains. At these sites, TLRs interact with the TIR domain-containing adaptor protein (TIRAP), triggering a signaling casca...
Na minha lista:
| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5320522/ https://ncbi.nlm.nih.gov/pubmed/28225045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43043 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|