TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation

Transmembrane B cell lymphoma 2-associated X protein inhibitor motif-containing (TMBIM) 6, a Ca(2+) channel-like protein, is highly up-regulated in several cancer types. Here, we show that TMBIM6 is closely associated with survival in patients with cervical, breast, lung, and prostate cancer. TMBIM6...

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Publicado en:Nat Commun
Autores principales: Kim, Hyun-Kyoung, Bhattarai, Kashi Raj, Junjappa, Raghu Patil, Ahn, Jin Hee, Pagire, Suvarna H., Yoo, Hyun Ju, Han, Jaeseok, Lee, Duckgue, Kim, Kyung-Woon, Kim, Hyung-Ryong, Chae, Han-Jung
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7419509/
https://ncbi.nlm.nih.gov/pubmed/32782388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17802-4
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