IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases

Inositol-requiring transmembrane kinase/endoribonuclease 1α (IRE1α) is the most prominent and evolutionarily conserved endoplasmic reticulum (ER) membrane protein. This transduces the signal of misfolded protein accumulation in the ER, named as ER stress, to the nucleus as “unfolded protein response...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Raghu Patil Junjappa, Prakash Patil, Kashi Raj Bhattarai, Hyung-Ryong Kim, Han-Jung Chae
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018-06-01
Colección:Frontiers in Immunology
Materias:
autoimmune diseases
cytokines
inflammation
IRE1α
regulated IRE1α-dependent decay
unfolded protein response signaling pathways
Acceso en línea:https://www.frontiersin.org/article/10.3389/fimmu.2018.01289/full
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares