IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases

Inositol-requiring transmembrane kinase/endoribonuclease 1α (IRE1α) is the most prominent and evolutionarily conserved endoplasmic reticulum (ER) membrane protein. This transduces the signal of misfolded protein accumulation in the ER, named as ER stress, to the nucleus as “unfolded protein response...

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Vydáno v:Front Immunol
Hlavní autoři: Junjappa, Raghu Patil, Patil, Prakash, Bhattarai, Kashi Raj, Kim, Hyung-Ryong, Chae, Han-Jung
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997832/
https://ncbi.nlm.nih.gov/pubmed/29928282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01289
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